Abstract
Here, we report a case of chronic granulomatous tubulo-interstitial nephritis related to atazanavir crystals in a HIV type-1-infected patient. Renal function in this patient was partially recovered after atazanavir withdrawal and steroid therapy. Many reports have described atazanavir-associated urolithiasis, but this is the first case that describes chronic granulomatous nephropathy.
MeSH terms
-
Africa, Northern / ethnology
-
Atazanavir Sulfate
-
Crystallization
-
Drug Therapy, Combination / adverse effects*
-
France
-
Granulomatous Disease, Chronic / chemically induced*
-
Granulomatous Disease, Chronic / physiopathology
-
HIV Infections / drug therapy
-
HIV Infections / pathology
-
HIV Protease Inhibitors / administration & dosage
-
HIV Protease Inhibitors / adverse effects*
-
HIV-1*
-
Humans
-
Male
-
Middle Aged
-
Nephritis, Interstitial / chemically induced*
-
Nephritis, Interstitial / physiopathology
-
Oligopeptides / administration & dosage
-
Oligopeptides / adverse effects*
-
Pyridines / administration & dosage
-
Pyridines / adverse effects*
-
Ritonavir / administration & dosage
-
Ritonavir / therapeutic use
Substances
-
HIV Protease Inhibitors
-
Oligopeptides
-
Pyridines
-
Atazanavir Sulfate
-
Ritonavir