Abstract
The autoxidative annulation cascade promoted by an α-cyano β-TMS-capped alkynyl cycloalkanone system under catalysis with pyridine in one oxygen atmosphere has proven to be highly viable. On the basis of this newly developed protocol, a variety of highly functionalized bicyclic frameworks can be effectively constructed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Combinatorial Chemistry Techniques
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Ketones / chemical synthesis*
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Ketones / chemistry*
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Molecular Structure
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Nitriles / chemical synthesis*
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Nitriles / chemistry*
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Pyridines / chemistry
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Stereoisomerism
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Trimethylsilyl Compounds / chemical synthesis*
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Trimethylsilyl Compounds / chemistry*
Substances
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Alkynes
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Ketones
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Nitriles
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Pyridines
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Trimethylsilyl Compounds
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pyridine