Nicorandil-induced rectovaginal fistula

Am J Obstet Gynecol. 2011 Apr;204(4):e5-6. doi: 10.1016/j.ajog.2010.12.035.

Abstract

An 82-year-old woman was admitted with feculent vaginal discharge and bleeding per vagina. Investigations revealed the presence of a rectovaginal fistula with no obvious etiology. Due to the surgical team's previous experience with nicorandil-induced ulceration, the drug was stopped. The rectovaginal fistula healed completely within 6 months.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Arrhythmia Agents / administration & dosage
  • Anti-Arrhythmia Agents / adverse effects*
  • Female
  • Gynecological Examination
  • Humans
  • Nicorandil / administration & dosage
  • Nicorandil / adverse effects*
  • Rectovaginal Fistula / chemically induced*
  • Sigmoidoscopy

Substances

  • Anti-Arrhythmia Agents
  • Nicorandil