Abstract
The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.
Publication types
-
Research Support, N.I.H., Extramural
MeSH terms
-
Base Sequence
-
Boronic Acids / chemistry*
-
Click Chemistry*
-
Copper / chemistry
-
DNA / chemical synthesis*
-
DNA / chemistry*
-
Oligodeoxyribonucleotides / chemical synthesis
-
Oligodeoxyribonucleotides / chemistry
-
Oligodeoxyribonucleotides / genetics
Substances
-
Boronic Acids
-
Oligodeoxyribonucleotides
-
Copper
-
DNA