Unraveling epigenetic landscapes: the enigma of enhancers

Irene Cantone; Amanda G Fisher

doi:10.1016/j.stem.2011.01.005

Unraveling epigenetic landscapes: the enigma of enhancers

Cell Stem Cell. 2011 Feb 4;8(2):128-9. doi: 10.1016/j.stem.2011.01.005.

Authors

Irene Cantone¹, Amanda G Fisher

Affiliation

¹ Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, UK.

PMID: 21295268
DOI: 10.1016/j.stem.2011.01.005

Abstract

In recent publications in Nature and PNAS, Rada-Iglesias et al. (2010) and Creyghton et al. (2010) have uncovered unique chromatin signatures of developmental enhancers marking active, primed, or silent genes in human and mouse embryonic stem cells.

Publication types

Comment

Grants and funding

MC_U120027516/MRC_/Medical Research Council/United Kingdom