Prevalence of beryllium sensitization among Department of Defense conventional munitions workers at low risk for exposure

J Occup Environ Med. 2011 Mar;53(3):258-65. doi: 10.1097/JOM.0b013e31820a408a.

Abstract

Objective: To estimate the prevalence of beryllium sensitization among former and current Department of Defense workers from a conventional munitions facility.

Methods: Participants were screened by using Beryllium Lymphocyte Proliferation Test. Those sensitized were offered clinical evaluation for chronic beryllium disease.

Results: Eight (1.5%) of 524 screened workers were found sensitized to beryllium. Although the confidence interval was wide, the results suggested a possibly higher risk of sensitization among workers exposed to beryllium by occasional resurfacing of copper-2% beryllium alloy tools compared with workers with the lowest potential exposure (odds ratio = 2.6; 95% confidence interval, 0.23-29.9).

Conclusions: The findings from this study suggest that Department of Defense workers with low overall exposure to beryllium had a low prevalence of beryllium sensitization. Sensitization rates might be higher where higher beryllium exposures presumably occurred, although this study lacked sufficient power to confirm this.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Beryllium / adverse effects*
  • Cohort Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nuclear Weapons*
  • Occupational Diseases / diagnosis
  • Occupational Diseases / epidemiology*
  • Occupational Exposure / adverse effects*
  • Prevalence
  • Risk
  • Risk Factors
  • United States
  • United States Department of Defense*

Substances

  • Beryllium