A novel aporphine alkaloid from Magnolia officinalis

Zuo-Fu Guo; Xiao-Bing Wang; Jian-Guang Luo; Jun Luo; Jun-Song Wang; Ling-Yi Kong

doi:10.1016/j.fitote.2011.01.021

A novel aporphine alkaloid from Magnolia officinalis

Fitoterapia. 2011 Jun;82(4):637-41. doi: 10.1016/j.fitote.2011.01.021. Epub 2011 Feb 1.

Authors

Zuo-Fu Guo¹, Xiao-Bing Wang, Jian-Guang Luo, Jun Luo, Jun-Song Wang, Ling-Yi Kong

Affiliation

¹ Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China.

PMID: 21291961
DOI: 10.1016/j.fitote.2011.01.021

Abstract

A novel aporphine alkaloid, magnofficine (1), has been isolated from the root barks of the Chinese medicinal plant Magnolia officinalis, along with seven known compounds. Elucidations of their structures were achieved by spectroscopic methods. Magnofficine is the first example of an adduct of aporphine alkaloid and 4-hydroxyphenethylamino bridged by a methylene.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aporphines / chemistry
Aporphines / isolation & purification*
Magnolia / chemistry*
Molecular Structure
Plant Bark / chemistry
Plant Roots / chemistry

Substances

Aporphines
magnofficine