Natural history of Fabry disease

Excerpt

Fabry disease is an X-linked condition that affects both men and women. The manifestations of this complex disease are progressive and multisystemic. The classic form is seen in both males and females, although the manifestations are often less severe in females and disease progression is generally delayed compared with males. This chapter describes the natural history of the classic form of the disease, as well as the different signs and symptoms in females, and atypical late-onset disease in males.