Direct monitoring of the inhibition of protein-protein interactions in cells by translocation of PKCδ fusion proteins

Angew Chem Int Ed Engl. 2011 Feb 7;50(6):1314-7. doi: 10.1002/anie.201005333. Epub 2011 Jan 5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Green Fluorescent Proteins / genetics
  • Green Fluorescent Proteins / metabolism
  • Humans
  • Protein Binding
  • Protein Interaction Mapping / methods*
  • Protein Kinase C-delta / chemistry
  • Protein Kinase C-delta / genetics
  • Protein Kinase C-delta / metabolism*
  • Proto-Oncogene Proteins c-mdm2 / genetics
  • Proto-Oncogene Proteins c-mdm2 / metabolism
  • Recombinant Fusion Proteins / chemistry
  • Recombinant Fusion Proteins / genetics
  • Recombinant Fusion Proteins / metabolism
  • Tacrolimus / chemistry
  • Tacrolimus Binding Protein 1A / genetics
  • Tacrolimus Binding Protein 1A / metabolism
  • Tumor Suppressor Protein p53 / genetics
  • Tumor Suppressor Protein p53 / metabolism

Substances

  • Recombinant Fusion Proteins
  • Tumor Suppressor Protein p53
  • Green Fluorescent Proteins
  • Proto-Oncogene Proteins c-mdm2
  • Protein Kinase C-delta
  • Tacrolimus Binding Protein 1A
  • Tacrolimus