Abstract
A new compound, 11-O-(3'-O-methylgalloyl)-bergenin (1), along with 11 known compounds (2-12), has been isolated from the rhizome of Astilbe chinensis. The chemical structure of compound 1 was determined by IR, MS, and NMR spectral data. All compounds were evaluated for the cytotoxic activity in vitro, and compound 4 showed a moderate cytotoxic activity against HepG2 cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Benzopyrans / chemistry
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Benzopyrans / isolation & purification*
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Gallic Acid / analogs & derivatives*
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Gallic Acid / chemistry
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Gallic Acid / isolation & purification
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Hep G2 Cells
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Humans
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Molecular Structure
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Oleanolic Acid / analogs & derivatives*
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Oleanolic Acid / chemistry
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Oleanolic Acid / isolation & purification
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Oleanolic Acid / pharmacology
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Plants, Medicinal / chemistry*
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Rhizome / chemistry
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Saxifragaceae / chemistry*
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Stereoisomerism
Substances
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11-O-(3'-methylgalloyl)bergenin
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3-hydroxyolean-12-en-27-oic acid
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Antineoplastic Agents, Phytogenic
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Benzopyrans
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Drugs, Chinese Herbal
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Gallic Acid
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Oleanolic Acid