Abstract
In this study, the fungistatic activity of Bacillus cereus cereulide-producing strains was demonstrated against nine fungal species. The role of cereulide was confirmed using plasmid-cured derivatives and ces knockout mutants. The fungistatic spectra of cereulide and valinomycin, a chemically related cyclododecadepsipeptide, were also compared and found to be similar but distinct.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / pharmacology*
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Bacillus cereus / metabolism*
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Depsipeptides / pharmacology*
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Fungi / drug effects*
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Fungi / growth & development
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Gene Deletion
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Genes, Bacterial
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Microbial Sensitivity Tests
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Plasmids
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Valinomycin / pharmacology
Substances
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Antifungal Agents
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Depsipeptides
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cereulide
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Valinomycin