Infiltrative lung diseases in pregnancy

Clin Chest Med. 2011 Mar;32(1):133-146. doi: 10.1016/j.ccm.2010.11.006.

Abstract

Pregnancy may affect the diagnosis, management, and outcome of infiltrative lung disease (ILD). Conversely, ILD may affect pregnancy. ILD may occur as a result of drugs administered commonly or specifically during pregnancy. Most ILDs predominate in patients older than 40 years and are thus rare in pregnant women. During pregnancy ILD may arise de novo and preexisting ILD may be exacerbated or significantly worsened. Some ILDs generally do not alter the management of pregnancy, labor, or delivery. Preexisting ILD no longer contraindicates pregnancy systematically, but thorough evaluation of ILD before pregnancy is required to identify potential contraindications and adapt monitoring.

Publication types

  • Review

MeSH terms

  • Connective Tissue Diseases / complications
  • Connective Tissue Diseases / drug therapy
  • Connective Tissue Diseases / epidemiology
  • Connective Tissue Diseases / physiopathology
  • Female
  • Fertility Agents, Female / adverse effects
  • Histiocytosis, Langerhans-Cell / diagnosis
  • Humans
  • Idiopathic Interstitial Pneumonias / diagnosis
  • Idiopathic Interstitial Pneumonias / therapy
  • Lung Diseases, Interstitial* / epidemiology
  • Lung Diseases, Interstitial* / etiology
  • Lung Diseases, Interstitial* / physiopathology
  • Lung Diseases, Interstitial* / therapy
  • Lymphangioleiomyomatosis / diagnosis
  • Lymphangioleiomyomatosis / epidemiology
  • Lymphangioleiomyomatosis / therapy
  • Pregnancy
  • Pregnancy Complications* / epidemiology
  • Pregnancy Complications* / etiology
  • Pregnancy Complications* / physiopathology
  • Pregnancy Complications* / therapy
  • Pregnancy Outcome
  • Pulmonary Alveolar Proteinosis / diagnosis
  • Pulmonary Alveolar Proteinosis / therapy
  • Pulmonary Edema / diagnosis
  • Pulmonary Edema / etiology
  • Pulmonary Edema / therapy
  • Pulmonary Eosinophilia / diagnosis
  • Pulmonary Eosinophilia / drug therapy
  • Risk Factors
  • Sarcoidosis, Pulmonary / drug therapy
  • Sarcoidosis, Pulmonary / epidemiology
  • Sarcoidosis, Pulmonary / physiopathology
  • Systemic Vasculitis / drug therapy
  • Systemic Vasculitis / epidemiology
  • Systemic Vasculitis / physiopathology

Substances

  • Fertility Agents, Female