Development of an optical imaging platform for functional imaging of small animals using wide-field excitation

Biomed Opt Express. 2010 Jul 15;1(1):143-156. doi: 10.1364/BOE.1.000143.

Abstract

The design and characterization of a time-resolved functional imager using a wide-field excitation scheme for small animal imaging is described. The optimal operation parameters are established based on phantom studies. The performance of the platform for functional imaging and the simultaneous 3D reconstruction of absorption and scattering coefficients is investigated in vitro.