Applications of X-ray scattering in pharmaceutical science

Int J Pharm. 2011 Sep 30;417(1-2):101-11. doi: 10.1016/j.ijpharm.2011.01.022. Epub 2011 Jan 21.

Abstract

The use of X-ray scattering techniques in pharmaceutical science is increasing, in part through increased collaborations with the materials science community, and through increased availability of instrumentation, particularly synchrotron sources. The ability to understand not only the biopharmaceutical outcome, but also arguably, more importantly, the structural aspects of drugs and drug delivery systems, is essential to progressing pharmaceutical science; this review serves as an introduction to the major techniques and the wide range of areas in which X-ray scattering may be applied in understanding and controlling structure in pharmaceutical systems.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems / methods*
  • Pharmaceutical Preparations / chemistry*
  • X-Ray Diffraction / methods*

Substances

  • Pharmaceutical Preparations