Abstract
A new synthetic route to pyrrolopyridinol antioxidants from easily accessible pyridoxine was developed which includes phase-transfer catalytic alkylation and intramolecular Cu(I)-catalyzed amination as key steps.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Hydroxylation
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Molecular Structure
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Pyridines / chemistry*
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Pyridoxine / chemistry*
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Pyrroles / chemistry*
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Stereoisomerism
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alpha-Tocopherol / analogs & derivatives*
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alpha-Tocopherol / chemical synthesis
Substances
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Pyridines
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Pyrroles
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alpha-Tocopherol
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Pyridoxine