Outbreak of West Nile virus infection in humans, Romania, July to October 2010

A Sirbu; C S Ceianu; R I Panculescu-Gatej; A Vazquez; A Tenorio; R Rebreanu; M Niedrig; G Nicolescu; A Pistol

Outbreak of West Nile virus infection in humans, Romania, July to October 2010

Euro Surveill. 2011 Jan 13;16(2):19762.

Authors

A Sirbu¹, C S Ceianu, R I Panculescu-Gatej, A Vazquez, A Tenorio, R Rebreanu, M Niedrig, G Nicolescu, A Pistol

Affiliation

¹ National Institute of Public Health - National Centre for Surveillance and Control of Communicable Diseases, Bucharest, Romania. anca.sirbu@insp.gov.ro

PMID: 21251489

Abstract

A total of 57 cases of West Nile virus infection (54 with neuroinvasive infection and three with fever) were identified in Romania between July and October 2010.The median age of the cases was 53.4 years, with the highest incidence in the age group 60–69 years.The case fatality rate was 8.8%. Cases were distributed in 19 districts in the southern, western, central and eastern parts of the country. Molecular investigation revealed lineage 2 West Nile virus, related to the Volgograd 2007 strain.

MeSH terms

Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Antibodies, Viral* / blood
Antibodies, Viral* / cerebrospinal fluid
Disease Outbreaks*
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Incidence
Male
Middle Aged
Polymerase Chain Reaction
Romania / epidemiology
Sex Distribution
West Nile Fever / diagnosis
West Nile Fever / epidemiology*
West Nile virus / genetics
West Nile virus / isolation & purification*
Young Adult

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M