Multifunctional gold nanoshells on silica nanorattles: a platform for the combination of photothermal therapy and chemotherapy with low systemic toxicity

Angew Chem Int Ed Engl. 2011 Jan 24;50(4):891-5. doi: 10.1002/anie.201002820. Epub 2010 Nov 25.

Authors

Huiyu Liu¹, Dong Chen, Linlin Li, Tianlong Liu, Longfei Tan, Xiaoli Wu, Fangqiong Tang

Affiliation

¹ Laboratory of Controllable Preparation and Application of Nanomaterials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.

PMID: 21246685
DOI: 10.1002/anie.201002820

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Combined Chemotherapy Protocols / chemistry
Antineoplastic Combined Chemotherapy Protocols / pharmacology*
Antineoplastic Combined Chemotherapy Protocols / toxicity
Carcinoma, Hepatocellular / drug therapy*
Cell Proliferation / drug effects
Drug Screening Assays, Antitumor
Gold / chemistry
Gold / pharmacology*
Gold / toxicity
Humans
Liver Neoplasms / drug therapy*
Mice
Nanoparticles / chemistry*
Nanoparticles / toxicity
Particle Size
Phototherapy
Porosity
Silicon Dioxide / chemistry
Silicon Dioxide / pharmacology*
Silicon Dioxide / toxicity
Surface Properties

Substances

Gold
Silicon Dioxide