Abstract
Clozapine-induced sialorrhea (CIS) is a frequently occurring debilitating adverse effect. Although various treatment options exist, none has been proved to be distinctly superior to others. We report a case of CIS that responded to low dose of trihexyphenidyl (2 mg/day).
MeSH terms
-
Adult
-
Antipsychotic Agents / adverse effects*
-
Clozapine / adverse effects*
-
Humans
-
Male
-
Muscarinic Antagonists / administration & dosage*
-
Sialorrhea / chemically induced
-
Sialorrhea / drug therapy*
-
Treatment Outcome
-
Trihexyphenidyl / administration & dosage*
Substances
-
Antipsychotic Agents
-
Muscarinic Antagonists
-
Trihexyphenidyl
-
Clozapine