Clustogenesis level in children with gastroduodenal diseases

Bull Exp Biol Med. 2010 Oct;149(4):431-3. doi: 10.1007/s10517-010-0963-7.
[Article in English, Russian]

Abstract

The mean count of cells with chromosome aberrations increased in a 72-h culture of peripheral blood lymphocytes of children with Helicobacter pylori-associated gastroduodenal diseases. After eradication therapy, intensification of clastogenesis was observed in the majority of children. Addition of vetoron to the treatment protocols reduced manifestations of clastogenesis.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Chromosome Aberrations / statistics & numerical data*
  • Chromosome Disorders / prevention & control
  • Duodenitis / complications
  • Female
  • Gastritis / complications
  • Helicobacter Infections / blood
  • Helicobacter Infections / drug therapy
  • Helicobacter Infections / genetics*
  • Helicobacter pylori
  • Humans
  • Male
  • beta Carotene / therapeutic use

Substances

  • beta Carotene