Experimental Toxocara cati infection in gerbils and rats

Korean J Parasitol. 2010 Dec;48(4):331-3. doi: 10.3347/kjp.2010.48.4.331. Epub 2010 Dec 16.

Abstract

Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.

Keywords: Mongolian gerbil; Toxocara cati; Wistar rat; experimental infection.

MeSH terms

  • Animal Structures / parasitology
  • Animals
  • Disease Models, Animal*
  • Gerbillinae
  • Histocytochemistry
  • Male
  • Microscopy
  • Rats
  • Rats, Wistar
  • Toxocara / pathogenicity*
  • Toxocariasis / parasitology*
  • Toxocariasis / pathology*