Higher number of stem cells in the bone marrow of circulating low Igf-1 level Laron dwarf mice--novel view on Igf-1, stem cells and aging

Leukemia. 2011 Apr;25(4):729-33. doi: 10.1038/leu.2010.314. Epub 2011 Jan 14.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging / physiology*
  • Animals
  • Bone Marrow / metabolism*
  • DNA Methylation
  • Embryonic Stem Cells / cytology*
  • Embryonic Stem Cells / metabolism
  • Hematopoietic Stem Cells / cytology*
  • Hematopoietic Stem Cells / metabolism
  • Insulin-Like Growth Factor I / metabolism*
  • Laron Syndrome / physiopathology*
  • Mice
  • Mice, Inbred C57BL
  • Octamer Transcription Factor-3 / genetics
  • Promoter Regions, Genetic

Substances

  • Octamer Transcription Factor-3
  • Pou5f1 protein, mouse
  • Insulin-Like Growth Factor I