The diagnostic threshold of generalized anxiety disorder in the community: a developmental perspective

J Psychiatr Res. 2011 Jul;45(7):962-72. doi: 10.1016/j.jpsychires.2010.12.007. Epub 2011 Jan 12.

Abstract

Discussion surrounds the question as to whether criteria for generalized anxiety disorder (GAD) should change, particularly in youth. This study examines the effects of possible criteria changes on GAD prevalence and clinical correlates. DSM-IV GAD was assessed using the M-CIDI in a community sample of adolescents and young adults. Diagnostic thresholds were modified in two age spans (9-20 and 21-34 years) using a person-by-year data file (N = 38,534 cases). Relaxing the duration or excessiveness criteria led to the most pronounced changes in GAD prevalence, while relaxing frequency, uncontrollability, or associated-symptom criteria had smaller effects. A lower duration requirement increased rates more in older than younger age spans. Opposite effects occurred for changes in associated-symptoms or clinical-significance criteria. Broader GAD definitions identified cases in both age spans that appeared mostly milder than DSM-IV cases but that still differed from non-GAD cases in various clinical factors and validators. Developmental aspects require stronger consideration in future diagnostic systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Anxiety Disorders / diagnosis*
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / genetics
  • Anxiety Disorders / psychology
  • Child
  • Comorbidity
  • Cross-Sectional Studies
  • Diagnostic and Statistical Manual of Mental Disorders
  • Genetic Predisposition to Disease / genetics
  • Germany
  • Humans
  • Life Change Events
  • Personality Inventory / statistics & numerical data
  • Prospective Studies
  • Psychometrics
  • Stress Disorders, Post-Traumatic / diagnosis
  • Stress Disorders, Post-Traumatic / epidemiology
  • Stress Disorders, Post-Traumatic / genetics
  • Stress Disorders, Post-Traumatic / psychology
  • Young Adult