Recurrent laryngeal papillomatosis: successful treatment with human papillomavirus vaccination

Arch Dis Child. 2011 May;96(5):476-7. doi: 10.1136/adc.2010.198184. Epub 2011 Jan 10.

Abstract

The authors describe the case of a 5-year-old girl with recurrent laryngeal papillomatosis (RLP) due to human papillomavirus (HPV) type 11, who required frequent surgical treatment. Complete recovery occurred after HPV vaccination (Gardasil). Confirmed remission of RLP has continued during the 17 months of follow-up since vaccination. The authors conclude that HPV vaccination may represent a new therapeutic option in this situation.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
  • Humans
  • Laryngeal Neoplasms* / prevention & control
  • Laryngeal Neoplasms* / surgery
  • Laryngeal Neoplasms* / virology
  • Papilloma* / prevention & control
  • Papilloma* / surgery
  • Papilloma* / virology
  • Papillomavirus Vaccines*
  • Secondary Prevention

Substances

  • Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
  • Papillomavirus Vaccines

Supplementary concepts

  • Laryngeal papillomatosis