Abstract
A new series of new hetero-bimetallic complexes containing iron and ruthenium of the general formula [RuCl(CO)(B)(EPh3)(L)] (where E=P or As; B=PPh3, AsPh3, py or pip; L=ferrocene derived monobasic bidentate thiosemicarbazone ligand) have been synthesized by the reaction between ferrocene-derived thiosemicarbazones and ruthenium(II) complexes of the type [RuHCl(CO)(B)(EPh3)2] (where E=P or As; B=PPh3, AsPh3, py or pip). The new complexes have been characterized by elemental analyses, IR, electronic, NMR (1H, 13C and 31P), EXAFS (extended X-ray absorption fine structure spectroscopy) and cyclic voltammetric techniques. Antibacterial activity of the new complexes has been screened against Escherichia coli, Vibrio cholerae, and Pseudomonas aeruginosa species.
Copyright © 2010 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology
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Arsenicals / chemistry
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Arsenicals / pharmacology*
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Electrochemical Techniques / methods*
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Escherichia coli / drug effects
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Ferrous Compounds / chemistry*
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Ligands
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Organophosphorus Compounds / chemistry
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Organophosphorus Compounds / pharmacology*
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Pseudomonas aeruginosa / drug effects
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Ruthenium / pharmacology*
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Schiff Bases
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Spectroscopy, Fourier Transform Infrared
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Thiosemicarbazones / chemistry
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Thiosemicarbazones / pharmacology*
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Vibrio cholerae / drug effects
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X-Ray Absorption Spectroscopy*
Substances
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Anti-Bacterial Agents
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Arsenicals
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Ferrous Compounds
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Ligands
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Organophosphorus Compounds
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Schiff Bases
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Thiosemicarbazones
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triphenylphosphine
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Ruthenium
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arsine