Trinuclear rare earth metal complexes based on 1,3,5-triamino-1,3,5-trideoxy-cis inositol as catalysts for the hydrolysis of phosphodiesters

Dalton Trans. 2011 Feb 14;40(6):1230-2. doi: 10.1039/c0dt01257b. Epub 2011 Jan 6.

Abstract

Trinuclear rare-earth metal complexes [M₃(taciH₋₃)₂](3+) (M = La(3+), Y(3+)), based on a rigid polyamino-polyalcohol ligand 1,3,5-triamino-1,3,5-trideoxy-cis-inositol (taci), are proven to be efficient catalysts for the hydrolysis of 2-hydroxypropyl-4-nitrophenyl phophate (HPNP), a commonly used RNA model system.

MeSH terms

  • Catalysis
  • Coordination Complexes / chemistry*
  • Hydrogen-Ion Concentration
  • Hydrolysis
  • Inositol / analogs & derivatives*
  • Inositol / chemistry
  • Kinetics
  • Metals, Rare Earth / chemistry*
  • Organophosphates
  • Organophosphorus Compounds / chemistry

Substances

  • 1,3,5-triamino-1,3,5-trideoxy-inositol
  • 2-(hydroxypropyl)-4-nitrophenyl phosphate
  • Coordination Complexes
  • Metals, Rare Earth
  • Organophosphates
  • Organophosphorus Compounds
  • Inositol