5-Fluorouracil-based chemotherapy for colorectal cancer and MTHFR/MTRR genotypes

Br J Clin Pharmacol. 2011 Jul;72(1):162-3. doi: 10.1111/j.1365-2125.2010.03892.x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use*
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics
  • Czech Republic
  • Disease-Free Survival
  • Ferredoxin-NADP Reductase / genetics*
  • Fluorouracil / therapeutic use*
  • Genotype
  • Humans
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics*
  • Polymorphism, Genetic

Substances

  • Antimetabolites, Antineoplastic
  • methionine synthase reductase
  • Ferredoxin-NADP Reductase
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Fluorouracil