3-[5-(4-Fluoro-phen-yl)-1,3,4-thia-diazol-2-yl]-2-(4-methoxy-phen-yl)-1,3-thia-zolidin-4-one

Li-He Yin; Rong Wan; Feng Han; Bin Wang; Jin-Tang Wang

doi:10.1107/S1600536808019089

3-[5-(4-Fluoro-phen-yl)-1,3,4-thia-diazol-2-yl]-2-(4-methoxy-phen-yl)-1,3-thia-zolidin-4-one

Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 28;64(Pt 7):o1359. doi: 10.1107/S1600536808019089.

Authors

Li-He Yin¹, Rong Wan, Feng Han, Bin Wang, Jin-Tang Wang

Affiliation

¹ Department of Applied Chemistry, College of Science, Nanjing University of Technology, No. 5 Xinmofan Road, Nanjing, Nanjing 210009, People's Republic of China.

Abstract

The title compound, C(18)H(14)FN(3)O(2)S(2), was synthesized by the reaction of 5-(4-fluoro-phen-yl)-N-(4-methoxy-benzyl-idene)-1,3,4-thia-diazol-2-amine and mercaptoacetic acid. The thia-zolidinone ring adopts a twist conformation. The 4-methoxy-phenyl ring is almost perpendicular to the thia-diazole ring, making a dihedral angle of 88.4 (3)°. The 4-fluoro-phenyl ring is nearly coplanar with the thia-diazole ring, the dihedral angle being 6.8 (3)°. The crystal structure involves C-H⋯N, C-H⋯O and C-H⋯S hydrogen bonds.