Simultaneous assessment of pulsating and total blood in inflammatory skin lesions using functional diffuse reflectance spectroscopy in the visible range

J Biomed Opt. 2010 Nov-Dec;15(6):060507. doi: 10.1117/1.3524191.

Abstract

We present a simple and cost-effective optical technique for the simultaneous assessment of pulsating and total blood noninvasively in an inflammatory skin lesion. Acquisitions of diffuse reflectance spectra in the visible range at 6 Hz are used to trace the oscillating components of reflectance. Measurements on erythematous lesions from a UV insult show slow changing signal at about 0.1 Hz and heart-driven regular oscillations at about 1 Hz simultaneously. The results demonstrate the potential of the technique in monitoring both pulsating and steady components of the blood in inflammatory lesions of the skin.

MeSH terms

  • Blood Flow Velocity
  • Blood Volume Determination / methods*
  • Blood Volume*
  • Diagnosis, Computer-Assisted / methods*
  • Erythema / diagnosis*
  • Erythema / physiopathology*
  • Humans
  • Pulsatile Flow*
  • Skin / blood supply
  • Skin / physiopathology*
  • Spectrum Analysis / methods*