Abstract
Objectives:
This study evaluated the ability of a novel sol-gel bioactive glass, in conjunction with appropriate carrier vehicles, to reduce dentinal fluid flow, with an eye toward reducing dentinal hypersensitivity.
Methods:
Experiments were conducted to measure the reduction in tubule fluid flow after treatment of cut tooth surfaces with sol-gel bioactive glass particles in several carrier vehicles. Surfaces were also examined after exposure to brushing and acidic solutions. A non-bioactive particulate glass was compared.
Results:
Tubular occlusion produced by the bioactive glass was observed via SEM and a sustained reduction in hydrodynamic conductance was measured after exposure to various fluids and brushing.
Conclusions:
This new material may be used with the tested carriers to significantly and durably reduce tubule fluid flow, ultimately resulting in reduced dentinal hypersensitivity.
Copyright © 2010 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Acids
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Beverages
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Biocompatible Materials / chemistry
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Biocompatible Materials / therapeutic use*
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Biomimetic Materials / chemistry
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Biomimetic Materials / therapeutic use*
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Carbonated Beverages
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Citrus paradisi
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Coffee
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Dentin / drug effects
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Dentin / ultrastructure
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Dentin Desensitizing Agents / chemistry
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Dentin Desensitizing Agents / therapeutic use*
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Dentinal Fluid / drug effects
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Drug Carriers / administration & dosage
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Ethanol / administration & dosage
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Glass* / chemistry
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Glycerol / administration & dosage
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Humans
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Materials Testing
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Methacrylates / administration & dosage
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Microscopy, Electron, Scanning
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Nanostructures / chemistry
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Nanostructures / therapeutic use*
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Phase Transition
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Propylene Glycol / administration & dosage
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Rheology
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Silicon Dioxide / therapeutic use
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Solvents / administration & dosage
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Spectroscopy, Fourier Transform Infrared
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Surface Properties
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Toothbrushing
Substances
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Acids
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Biocompatible Materials
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Coffee
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Dentin Desensitizing Agents
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Drug Carriers
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Methacrylates
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Solvents
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bioactive glass 58S
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Ethanol
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Propylene Glycol
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hydroxyethyl methacrylate
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Silicon Dioxide
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Glycerol