Primary precursor B cell lymphoblastic lymphoma of uterine corpus: case report and review of the literature

Arch Gynecol Obstet. 2011 Nov;284(5):1289-92. doi: 10.1007/s00404-010-1817-2. Epub 2010 Dec 31.

Abstract

Introduction: Primary lymphomas of the female genital tract are rare. Most involve the cervix rather than the uterine corpus. Many cases of primary endometrial lymphoma are diagnosed as diffuse large B cell type, whereas the precursor B cell lymphoblastic type is extremely rare.

Materials and methods: We report a case of precursor B cell lymphoblastic lymphoma of uterine corpus which was successfully treated with surgery and chemotherapy. Staging evaluation revealed tumor limited to the uterine corpus (stage I(E)). After receiving a total abdominal hysterectomy, bilateral salpingooophorectomy, lymph node dissection and combination chemotherapy, the patient is currently free of disease after follow-up of 42 months.

Conclusion: If correct diagnosis is established and appropriate therapy is chosen, the prognosis of precursor B-LBL of uterine corpus is expected to be good. The literature on primary precursor B cell lymphoblastic lymphoma of the uterine corpus is reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols
  • Combined Modality Therapy
  • Female
  • Humans
  • Hysterectomy / methods
  • Lymph Node Excision
  • Ovariectomy / methods
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / surgery
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Uterine Neoplasms / drug therapy
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery
  • Uterine Neoplasms / therapy*

Substances

  • Antineoplastic Agents