Replisome trafficking in growing vegetative hyphae of Streptomyces coelicolor A3(2)

J Bacteriol. 2011 Mar;193(5):1273-5. doi: 10.1128/JB.01326-10. Epub 2010 Dec 30.

Abstract

We observed movies of replisome trafficking during Streptomyces coelicolor growth. A replisome(s) in the spore served as a replication center(s) until hyphae reached a certain length, when a tip-proximal replisome formed and moved at a fixed distance behind the tip at a speed equivalent to the extension rate of the tip.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / metabolism
  • Cell Wall
  • DNA Replication
  • Gene Expression Regulation, Bacterial / physiology
  • Protein Transport / physiology*
  • Recombinant Fusion Proteins
  • Streptomyces coelicolor / cytology
  • Streptomyces coelicolor / genetics
  • Streptomyces coelicolor / metabolism*

Substances

  • Bacterial Proteins
  • Cell Cycle Proteins
  • DivIVA protein, bacteria
  • Recombinant Fusion Proteins