Foreign travel and decreased ciprofloxacin susceptibility in Salmonella enterica infections

Emerg Infect Dis. 2011 Jan;17(1):123-5. doi: 10.3201/eid1701.100999.

Abstract

To determine antimicrobial drug resistance patterns, we characterized nontyphoidal Salmonella enterica strains isolated in Liverpool, UK, January 2003 through December 2009. Decreased susceptibility to ciprofloxacin was found in 103 (20.9%) of 492 isolates. The lower susceptibility was associated with ciprofloxacin treatment failures and with particular serovars and phage types often acquired during foreign travel.

MeSH terms

  • Anti-Infective Agents / pharmacology*
  • Ciprofloxacin / pharmacology*
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Microbial Sensitivity Tests
  • Nalidixic Acid / pharmacology
  • Salmonella Infections / microbiology*
  • Salmonella enterica / classification
  • Salmonella enterica / drug effects*
  • Salmonella enteritidis / drug effects
  • Salmonella typhimurium / drug effects
  • Travel*
  • United Kingdom

Substances

  • Anti-Infective Agents
  • Nalidixic Acid
  • Ciprofloxacin