The prognosis of glycoregulation disturbances and insulin secretion in alcoholic and C virus liver cirrhosis

Rom J Intern Med. 2009;47(4):387-92.

Abstract

We studied 49 alcoholic and viral C liver cirrhosis, over a period of 5 years, we evaluated OGTT, HOMA-IR, HOMA-beta, child score, diabetes mellitus and liver cirrhosis complications and survival. Both insulin resistance and lower insulin secretion in liver cirrhosis are important determinants of the degree of oral glucose tolerance. There is a correlation between the bad prognosis in patients with cirrhosis and glycoregulation disturbances, especially in those with alcoholic etiology.

MeSH terms

  • Diabetes Complications / complications
  • Diabetes Complications / diagnosis*
  • Diabetes Complications / mortality
  • Female
  • Glucose Intolerance / complications
  • Glucose Intolerance / diagnosis*
  • Glucose Intolerance / mortality
  • Glucose Tolerance Test
  • Hepatitis C / complications
  • Hepatitis C / metabolism*
  • Hepatitis C / mortality
  • Humans
  • Insulin Resistance*
  • Liver Cirrhosis, Alcoholic / complications
  • Liver Cirrhosis, Alcoholic / metabolism*
  • Liver Cirrhosis, Alcoholic / mortality
  • Male
  • Predictive Value of Tests
  • Prognosis
  • Survival Rate