Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes

Antonio Perino; Lucia Giovannelli; Rosaria Schillaci; Giovanni Ruvolo; Francesco Paolo Fiorentino; Pietro Alimondi; Eleonora Cefalù; Piero Ammatuna

doi:10.1016/j.fertnstert.2010.11.047

Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes

Fertil Steril. 2011 Apr;95(5):1845-8. doi: 10.1016/j.fertnstert.2010.11.047. Epub 2010 Dec 17.

Authors

Antonio Perino¹, Lucia Giovannelli, Rosaria Schillaci, Giovanni Ruvolo, Francesco Paolo Fiorentino, Pietro Alimondi, Eleonora Cefalù, Piero Ammatuna

Affiliation

¹ Dipartimento Materno Infantile, University of Palermo, Palermo, Italy.

PMID: 21167483
DOI: 10.1016/j.fertnstert.2010.11.047

Abstract

A prospective study was performed to assess the relationship between human papillomavirus (HPV) infection in 199 infertile couples and outcome of assisted reproductive technologies (ARTs). A highly statistically significant correlation between pregnancy loss rate (proportion of pregnancies detected by β-hCG that did not progress beyond 20 weeks) and positive HPV DNA testing in the male partner of infertile couples, compared with HPV negatives, was observed (66.7% vs. 15%).

Publication types

Clinical Trial

MeSH terms

Adult
Alphapapillomavirus / physiology
Family Characteristics
Female
Fertilization in Vitro / methods*
Fertilization in Vitro / statistics & numerical data
Humans
Infectious Disease Transmission, Vertical / prevention & control
Infertility / complications*
Infertility / epidemiology
Infertility / therapy*
Infertility / virology
Male
Papillomavirus Infections / complications*
Papillomavirus Infections / epidemiology
Papillomavirus Infections / prevention & control
Papillomavirus Infections / transmission
Pregnancy
Pregnancy Outcome*
Treatment Outcome