Calcium-aluminium-phosphate cements (CAPCs) for biomedical applications, mainly intended for applications in the dental field as non-resorbable fillers, were obtained by reacting Ca-aluminates compounds, i.e. CaO·Al(2)O(3) (CA) and CaO·2 Al(2)O(3) (CA(2)), with Al(H(2)PO(4))(3) aqueous solution. Hydroxyapatite was also introduced as a bioactive dispersed phase. Suitable elements like Sr and La were used to increase the radiopacity of the set yielded pastes towards X-ray wavelength used in clinical diagnostic radiographic equipments. La and Sr doped Ca-aluminates powders have been synthesized by solid state reaction at 1,400°C from a mixture of CaCO(3), Al(2)O(3), La(2)O(3) and SrCO(3). The characteristics of the obtained powders were analyzed and related to the starting compositions and synthesis procedures. The microstructure, setting time, radiopacity and compressive strength of the CAPCs have been investigated and discussed.