The parametric optimization of Digital Backward Propagation (DBP) algorithm for mitigating fiber transmission impairments is proposed and numerically demonstrated for phase modulated signals in mixed-optical fiber transmission link. The optimization of parameters i.e. dispersion (D) and non-linear coefficient (γ) offer improved eye-opening (EO). We investigate the optimization of iterative and non-iterative symmetric split-step Fourier method (S-SSFM) for solving the inverse non-linear Schrödinger equation (NLSE). Optimized DBP algorithm, with step-size equal to fiber module length i.e. one calculation step per fiber span for obtaining higher computational efficiency, is implemented at the receiver as a digital signal processing (DSP) module. The system performance is evaluated by EO-improvement for diverse in-line compensation schemes. Using computationally efficient non-iterative symmetric split-step Fourier method (NIS-SSFM) upto 3.6 dB referenced EO-improvement can be obtained at 6 dBm signal launch power by optimizing and modifying DBP algorithm parameters, based on the characterization of the individual fiber types, in mixed-optical fiber transmission link.