Interneuronal membrane contacts and syncytial perforations in CA2 hippocampal area after brain trauma

Bull Exp Biol Med. 2010 Dec;150(1):100-3. doi: 10.1007/s10517-010-1080-3.

Abstract

Membranes of pyramid neuron bodies located in CA2 hippocampal area were studied by electron microscopy after gunshot craniocerebral injury. In control group, asynaptic contacts and interneuronal syncytial perforations forming from tight junctions were observed. Contacts and perforations increased in size after trauma. Their number was maximum after severe gunshot injury. They reached their maximal size on days 5-7 after the injury.

MeSH terms

  • Animals
  • Brain Injuries / pathology*
  • Brain Injuries / physiopathology*
  • CA2 Region, Hippocampal / pathology*
  • CA2 Region, Hippocampal / physiopathology*
  • Cell Membrane / pathology*
  • Interneurons / pathology*
  • Models, Biological
  • Rabbits
  • Tight Junctions / pathology