A case of dementia with Lewy bodies that temporarily showed symptoms similar to Creutzfeldt-Jakob disease

Psychogeriatrics. 2010 Dec;10(4):201-5. doi: 10.1111/j.1479-8301.2010.00336.x. Epub 2010 Nov 26.

Abstract

We discuss a case of a 67-year-old male with dementia with Lewy bodies (DLB) that was initially suspected as Creutzfeldt-Jakob disease (CJD) or another type of encephalopathy, because he showed rapidly progressive deterioration, myoclonus, gait disturbance and a decline in activities of daily living. The present study describes a clinically atypical case with probable DLB and reviews similar cases in the literature, and we propose a rapidly progressive clinical subtype of DLB.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain Ischemia / diagnosis
  • Cholinesterase Inhibitors / therapeutic use
  • Creutzfeldt-Jakob Syndrome / diagnosis*
  • Creutzfeldt-Jakob Syndrome / drug therapy
  • Creutzfeldt-Jakob Syndrome / psychology
  • Diagnosis, Differential
  • Donepezil
  • Hallucinations / diagnosis
  • Hallucinations / psychology
  • Humans
  • Indans / therapeutic use
  • Lewy Body Disease / diagnosis*
  • Lewy Body Disease / drug therapy
  • Lewy Body Disease / psychology
  • Male
  • Mental Status Schedule
  • Neuropsychological Tests
  • Occipital Lobe / diagnostic imaging
  • Parietal Lobe / diagnostic imaging
  • Piperidines / therapeutic use
  • Tomography, Emission-Computed, Single-Photon

Substances

  • Cholinesterase Inhibitors
  • Indans
  • Piperidines
  • Donepezil