Time-dependent effects of exposure to static magnetic field on glucose and lipid metabolism in rat

Gen Physiol Biophys. 2010 Dec;29(4):390-5. doi: 10.4149/gpb_2010_04_390.

Abstract

In the following study, we investigate the effects of static magnetic field (SMF) (128 mT, 1 h/day during 5 or 15 consecutive days) on anthropometric parameters, glucose and lipid metabolism in rats. Exposure to SMF during 5 days induced a decrease (-8%, p < 0.05) in relative liver weight and serum insulin concentration (-56%, p < 0.001), while blood glucose level was increased (+10%, p < 0.001). By contrast, the same treatment failed to alter body weight, relative kidney weight and levels of lactate, cholesterol, triglycerides and phospholipids. Exposure to SMF during 15 days induced a decrease (-15 %, p < 0.001) in body weight, liver weight (-15 %, p < 0.05), insulin concentration (-63%, p < 0.001), plasmatic lactate level (-55%, p < 0.05) and increased glucose (+24%, p < 0.001), cholesterol (+30%, p < 0.01,) and phospholipids levels (+58%, p < 0.001), whereas, triglycerides decreased (-28%, p < 0.001). These results showed that SMF effects on glucose and lipid metabolism are time-dependent.

MeSH terms

  • Animals
  • Blood Glucose / metabolism
  • Body Weight
  • Glucose / metabolism*
  • Kidney / anatomy & histology
  • Lipid Metabolism*
  • Liver / anatomy & histology
  • Magnetics*
  • Male
  • Organ Size
  • Rats
  • Rats, Wistar
  • Time Factors

Substances

  • Blood Glucose
  • Glucose