Reinforcement learning: a novel method for optimal control of propofol-induced hypnosis

Anesth Analg. 2011 Feb;112(2):360-7. doi: 10.1213/ANE.0b013e31820334a7. Epub 2010 Dec 14.

Abstract

Reinforcement learning (RL) is an intelligent systems technique with a history of success in difficult robotic control problems. Similar machine learning techniques, such as artificial neural networks and fuzzy logic, have been successfully applied to clinical control problems. Although RL presents a mathematically robust method of achieving optimal control in systems challenged with noise, nonlinearity, time delay, and uncertainty, no application of RL in clinical anesthesia has been reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anesthesia, Closed-Circuit*
  • Anesthetics, Intravenous / administration & dosage*
  • Anesthetics, Intravenous / pharmacokinetics
  • Artificial Intelligence*
  • Consciousness Monitors*
  • Dose-Response Relationship, Drug
  • Humans
  • Hypnosis, Anesthetic*
  • Intraoperative Period
  • Models, Theoretical*
  • Monitoring, Intraoperative* / instrumentation
  • Monitoring, Intraoperative* / methods
  • Pattern Recognition, Automated
  • Propofol / administration & dosage*
  • Propofol / pharmacokinetics
  • Signal Processing, Computer-Assisted

Substances

  • Anesthetics, Intravenous
  • Propofol