Management of ruptured retinal arterial macroaneurysm with intravitreal bevacizumab

Ophthalmic Surg Lasers Imaging. 2010 Aug 30:41 Online:e1-5. doi: 10.3928/15428877-20100830-07.

Abstract

The authors report the management of a ruptured retinal arterial macroaneurysm and associated hemorrhages with intravitreal injections of bevacizumab. A 79-year-old woman presented with a history of systemic arterial hypertension and a ruptured retinal arterial macroaneurysm with pre-retinal, intraretinal, and subretinal hemorrhages extending into the macula. Visual acuity at presentation was 20/400. The patient was treated with two intravitreal injections of bevacizumab at 4-week intervals. Steady clearing of the pre-retinal, intraretinal, and subretinal hemorrhages was observed with restoration of final visual acuity to 20/20 in the 12 months after the initial presentation. It appears that the novel application of intravitreal bevacizumab may be used in the treatment of ruptured retinal arterial macroaneurysm.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aneurysm, Ruptured / complications
  • Aneurysm, Ruptured / diagnosis
  • Aneurysm, Ruptured / drug therapy*
  • Aneurysm, Ruptured / physiopathology
  • Antibodies, Monoclonal / administration & dosage*
  • Antibodies, Monoclonal, Humanized
  • Bevacizumab
  • Drug Administration Schedule
  • Female
  • Fundus Oculi
  • Humans
  • Intravitreal Injections
  • Retinal Artery*
  • Retinal Hemorrhage / etiology
  • Retinal Hemorrhage / physiopathology
  • Tomography, Optical Coherence
  • Treatment Outcome
  • Ultrasonography
  • Visual Acuity / drug effects

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Bevacizumab