Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-κB precursor

Adv Exp Med Biol. 2011:691:95-106. doi: 10.1007/978-1-4419-6612-4_10.

Authors

Yelena Kravtsova-Ivantsiv¹, Shai Cohen, Aaron Ciechanover

Affiliation

¹ Cancer and Vascular Biology Center, The Rappaport Faculty of Medicine and Research Institute, Technion - Israel Institute of Technology, P.O. Box 9649, 31096 Haifa, Israel.

PMID: 21153313
DOI: 10.1007/978-1-4419-6612-4_10

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell-Free System
HEK293 Cells
Humans
Mutant Proteins / metabolism
NF-kappa B p50 Subunit / metabolism*
Polyubiquitin / metabolism*
Proteasome Endopeptidase Complex / metabolism*
Protein Binding
Protein Processing, Post-Translational*
Ubiquitination*

Substances

Mutant Proteins
NF-kappa B p50 Subunit
Polyubiquitin
Proteasome Endopeptidase Complex