Abstract
We found that the epigallocatechin gallate (EGCG)/epigallocatechin (EGC) ratio in a green tea (Camellia sinensis L.) extract was affected by the extraction temperature. The EGCG/EGC ratio in the 4 °C extract was around 1:3-4, whereas in the 100 °C extract, it was around 1:0.7. Oral administration of the mixture with a high EGC ratio (1:2-3 = EGCG/EGC) resulted in greater IgA production by murine Peyer's patch cells.
MeSH terms
-
Animals
-
Camellia sinensis / chemistry*
-
Catechin / analogs & derivatives
-
Catechin / analysis*
-
Catechin / isolation & purification
-
Catechin / pharmacology*
-
Chemical Fractionation / methods*
-
Female
-
Immunoglobulin A / immunology*
-
Immunologic Factors / analysis
-
Immunologic Factors / isolation & purification
-
Immunologic Factors / pharmacology
-
Mice
-
Mice, Inbred BALB C
-
Peyer's Patches / cytology
-
Peyer's Patches / drug effects
-
Peyer's Patches / immunology
-
Tea / chemistry*
-
Temperature*
Substances
-
Immunoglobulin A
-
Immunologic Factors
-
Tea
-
Catechin
-
epigallocatechin gallate
-
gallocatechol