Total synthesis of (-)-Przewalskin B

Jiyue Zheng; Xingang Xie; Changgui Zhao; Yongping He; Huaiji Zheng; Zhen Yang; Xuegong She

doi:10.1021/ol102593r

Total synthesis of (-)-Przewalskin B

Org Lett. 2011 Jan 21;13(2):173-5. doi: 10.1021/ol102593r. Epub 2010 Dec 9.

Authors

Jiyue Zheng¹, Xingang Xie, Changgui Zhao, Yongping He, Huaiji Zheng, Zhen Yang, Xuegong She

Affiliation

¹ State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.

PMID: 21141917
DOI: 10.1021/ol102593r

Abstract

The first total synthesis of (-)-Przewalskin B has been accomplished with an intramolecular nucleophilic acyl substitution (INAS) reaction and an intramolecular aldol condensation as key steps.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diterpenes / chemical synthesis*
Diterpenes / chemistry
Molecular Structure
Salvia / chemistry
Stereoisomerism

Substances

Diterpenes
Przewalskin B