Thiazole and oxazole alkaloids: isolation and synthesis

Mar Drugs. 2010 Nov 5;8(11):2755-80. doi: 10.3390/md8112755.

Abstract

Thiazoles, oxazole and their corresponding reduced derivatives, thiazolines and oxazolines, are found in marine sources exhibiting significant biological activities. The isolation, synthetic, and biological studies of these natural products, covering literature from January 2007 to June 2010, are summarized.

Keywords: marine; oxazole; thiazole.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkaloids* / chemical synthesis
  • Alkaloids* / isolation & purification
  • Alkaloids* / pharmacology
  • Animals
  • Biological Products / chemical synthesis
  • Biological Products / isolation & purification
  • Biological Products / pharmacology
  • Drug Design
  • Drug Discovery / methods
  • Humans
  • Oxazoles* / chemical synthesis
  • Oxazoles* / isolation & purification
  • Oxazoles* / pharmacology
  • Thiazoles* / chemical synthesis
  • Thiazoles* / isolation & purification
  • Thiazoles* / pharmacology

Substances

  • Alkaloids
  • Biological Products
  • Oxazoles
  • Thiazoles