Abstract
A three-gene operon, named yctCBA (Yersinia citrate transporter), induced by citrate and repressed by glucose was identified from a previously selected in vivo-induced (ivi) clone in the fish pathogen Yersinia ruckeri. Interestingly, despite being an ivi clone, the drastic growth reduction of the yctC mutant in the presence of citrate, and the relatively high content of this compound in rainbow trout serum, the operon was not required for virulence.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Citric Acid / metabolism*
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Fish Diseases / microbiology*
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Molecular Sequence Data
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Mutation
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Oncorhynchus mykiss / microbiology*
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Operon*
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Sequence Analysis, DNA
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Virulence
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Yersinia Infections / microbiology
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Yersinia Infections / veterinary*
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Yersinia ruckeri / genetics
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Yersinia ruckeri / growth & development
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Yersinia ruckeri / metabolism
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Yersinia ruckeri / pathogenicity*
Substances
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Bacterial Proteins
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Citric Acid