Effect of a new probiotic Saccharomyces cerevisiae strain on survival of Escherichia coli O157:H7 in a dynamic gastrointestinal model

Appl Environ Microbiol. 2011 Feb;77(3):1127-31. doi: 10.1128/AEM.02130-10. Epub 2010 Dec 3.

Abstract

Survival of Escherichia coli O157:H7 was investigated using a dynamic gastrointestinal model. A high bacterial mortality was observed in the stomach and duodenum. In contrast, bacteria grew in the distal parts of the small intestine. The coadministration of Saccharomyces cerevisiae CNCM I-3856 led to a significant reduction of bacterial resumption, maybe through ethanol production.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiosis*
  • Colony Count, Microbial
  • Escherichia coli O157 / drug effects*
  • Escherichia coli O157 / genetics
  • Escherichia coli O157 / growth & development*
  • Ethanol / metabolism
  • Ethanol / pharmacology
  • Gastrointestinal Tract / microbiology*
  • Humans
  • Microbial Viability
  • Probiotics / administration & dosage*
  • Probiotics / pharmacology*
  • Saccharomyces cerevisiae / growth & development*
  • Saccharomyces cerevisiae / metabolism

Substances

  • Ethanol