Editorial: 25-Hydroxycholesterol: a new life in immunology

J Leukoc Biol. 2010 Dec;88(6):1071-2. doi: 10.1189/jlb.0710418.

Abstract

A discussion on paper by Park and Scott revealing the signaling pathways leading to the synthesis of a potent immunoregulatory oxysterol by macrophage and dendritic cells.

Publication types

  • Comment
  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Dendritic Cells / metabolism
  • Humans
  • Hydroxycholesterols / metabolism*
  • Immune System / physiology*
  • Interferon-beta / genetics
  • Macrophages / metabolism
  • Mice
  • Steroid Hydroxylases / genetics
  • Toll-Like Receptors / physiology

Substances

  • Hydroxycholesterols
  • Toll-Like Receptors
  • 25-hydroxycholesterol
  • Interferon-beta
  • Steroid Hydroxylases
  • cholesterol 25-hydroxylase