Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance' by Calabrese et al

Hum Exp Toxicol. 2010 Dec;29(12):1016-7. doi: 10.1177/0960327110383626.

Abstract

Resveratrol, a grape skin and red wine-derived polyphenolic phytoalexin, exhibits hormetic action delivering numerous health benefits at lower doses while being detrimental at higher doses. Epidemiologic and clinical trials need to be based on the clear understanding of hormetic health benefits of resveratrol.

MeSH terms

  • Animals
  • Biomedical Research*
  • Cardiotonic Agents / administration & dosage*
  • Cardiotonic Agents / adverse effects
  • Cardiotonic Agents / pharmacology
  • Cardiovascular System / drug effects
  • Dose-Response Relationship, Drug*
  • Humans
  • Resveratrol
  • Stilbenes / administration & dosage*
  • Stilbenes / adverse effects
  • Stilbenes / pharmacology
  • Wine

Substances

  • Cardiotonic Agents
  • Stilbenes
  • Resveratrol