Fabrication of carbohydrate microarrays through boronate formation

Chem Commun (Camb). 2011 Jan 28;47(4):1187-9. doi: 10.1039/c0cc03816d. Epub 2010 Nov 26.

Abstract

A straightforward method for fabricating a stable and covalent carbohydrate microarray based on boronate formation between the hydroxyl groups of carbohydrate and boronic acid (BA) on the glass surface was used to identify carbohydrate-protein interactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boronic Acids / chemistry*
  • Carbohydrates / analysis*
  • Dextrans / chemistry
  • Fluorescein-5-isothiocyanate / chemistry
  • Glass / chemistry
  • Microarray Analysis / methods*
  • Surface Properties

Substances

  • Boronic Acids
  • Carbohydrates
  • Dextrans
  • Fluorescein-5-isothiocyanate